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KMID : 0860920190210020037
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Journal of the Korean Association EMG-Electrodiagnostic Medicine
2019 Volume.21 No. 2 p.37 ~ p.42
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Approach to Patients with Acquired Neuromuscular Junction Diseases
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Cho Jeong-Hee
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Abstract
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Neuromuscular junction (NMJ) diseases include myasthenia gravis, Lambert-Eaton myasthenic syndrome, botulism and congenital myasthenic syndromes. NMJ diseases have a wide range of clinical presentations. A common feature of these conditions is muscle weakness that predominates in certain muscle groups and fluctuates in response to effort and rest. The diagnosis of NMJ diseases is established by neurologic manifestations, serologic tests and neurophysiologic tests. The clinical presentation determines which diagnostic tests should be used in patients with these diseases. This review summarizes the approach to patients with acquired NMJ diseases.
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KEYWORD
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neuromuscular junction diseases, neurologic manifestations, serologic tests, neurophysiology
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